Steroids and derivatives
Medchemexpress LLC Estradiol 3-glucuronide | 15270-30-1 | 97.6% | 448.51 g/mol | C24H32O8 | 500 UG
Estradiol 3-glucuronide is the glucuronic acid conjugate of estradiol used as a research reagent and immunogen for studies of estrogen metabolism, antibody production, and radioimmunoassay. Supplied as a white to off-white solid for laboratory research use only.
- White to off-white solid suitable for biochemical assays.
- Used as an immunogen for antibody generation and radioimmunoassay studies.
- Applicable in research on estrogen metabolism and analytical detection methods.
- Typical purity approximately 97.6% by HPLC (batch dependent).
- Chemical formula C24H32O8; molecular weight 448.51 g/mol; CAS 15270-30-1.
- Store powder at -20°C; in solvent store at -80°C up to 6 months or -20°C for shorter term.
Medchemexpress LLC Dexamethasone palmitate | 14899-36-6 | 99.68% | 1 ML
Dexamethasone palmitate (DXP) is a prodrug of Dexamethasone (HY-14648) and can be utilized for inflammation research. It has demonstrated in vitro anti-inflammatory effects by decreasing LPS-induced MCP-1 and TNF-α concentration in RAW 264.7 cells. In vivo studies showed that a single intravitreal (IVT) injection resulted in distribution mostly in the vitreous, persisting for up to 9 months, and controlled VEGF-induced vascular hyperpermeability.
- Utilized for inflammation research
- Decreases LPS-induced MCP-1 and TNF-α concentration
- Shows sustained distribution in vitreous for up to 9 months
- Controls VEGF-induced vascular hyperpermeability
Medchemexpress LLC Dexamethasone palmitate | 14899-36-6 | 99.7% | 10 MG
Dexamethasone palmitate (DXP) is a proagent of Dexamethasone and can be used for inflammation research. This compound has demonstrated significant biological activity both in vitro and in vivo.
- Affects cytokine concentration of RAW 264.7 cells in vitro.
- Shows in vitro anti-inflammatory effects by decreasing LPS-induced MCP-1 and TNF-α concentration in RAW 264.7 cells.
- Exhibits different distribution in ocular tissue at various times during in vivo studies.
- Affects VEGF-induced vascular hyperpermeability in vivo.
Medchemexpress LLC Hydrocortisone hemisuccinate | 2203-97-6 | MFCD00046256 | 10 MG
Hydrocortisone hemisuccinate is a steroidal glucocorticoid research reagent used as an anti-inflammatory agent in research and analytical applications. It is supplied as solids and ready-to-use solutions for reconstitution and analytical work, and is intended for research use only (not for human consumption).
- Provides a soluble hemisuccinate ester of hydrocortisone for improved water solubility.
- Suitable as an analytical standard and research reagent.
- Available as solution formats and multiple solid quantities for flexibility in experiments.
- Contains identified molecular formula and molecular weight for analytical use.
Apexbio Technology LLC Dexamethasone phosphate disodium 2392-39-4 100mg
Dexamethasone phosphate disodium (CAS 2392-39-4) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid-mediated signaling pathways thereby regulating immune and inflammatory responses Dexamethasone phosphate disodium exerts its biological activity primarily by binding to the glucocorticoid receptor initiating nuclear translocation and influencing gene transcription to suppress the expression and secretion of pro-inflammatory cytokines and chemokines Based on these pharmacological properties dexamethasone phosphate disodium holds research potential in studying inflammatory conditions immune response processes and associated signaling cascades in vitro and in vivo
Medchemexpress LLC Dexamethasone (GMP) | 50-02-2 | MFCD00064136 | >99.8% | 392.46 | 50 MG
Dexamethasone (Hexadecadrol) (GMP) is a glucocorticoid receptor agonist produced using GMP guidelines. It functions as an auxiliary reagent for cell therapy manufacture.
- Increases myotubes formation and cytoplasmic lipid droplets accumulation
- Induces osteogenesis of chick periosteum cells
- Induces osteoblastic differentiation
- Stimulates differentiation of odontoblast-like cells
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 10 MG
Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. This product is a solid, appearing white to off-white in color, and is suitable for various research applications. It offers specific solubility characteristics in DMSO and has defined storage conditions to maintain its stability and efficacy.
- Synthetic glucocorticoid corticosteroid
- Corticosteroid ester
- Appears as a solid, white to off-white
- Solubility in DMSO is 125 mg/mL
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
Medchemexpress LLC Cortisone 21-acetate (Standard) | 50-04-4 | 99.4% | 402.48 | 100 MG
Cortisone acetate (Standard) is the analytical standard of Cortisone acetate, intended for research and analytical applications. It is an oxidized metabolite of Cortisol (a Glucocorticoid) and functions as an immunosuppressant and anti-inflammatory agent. At high concentrations, Cortisone acetate can partially interfere with the binding of Glucocorticoid to the Glucocorticoid-receptor.
- Grade of analytical standard, supplied as a reference standard assay.
- Commonly used in qualitative, quantitative, and methodological research experiments.
- Suitable for use in HPLC, GC, and MS.
- Acts as an immunosuppressant.
- Acts as an anti-inflammatory agent.
- Purity of 99.39%.
Selleck Chemical LLC Dexamethasone S1322-10g
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects Dexamethasone induces autophagy and mitophagy Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients
Medchemexpress LLC Hydrocortisone acepo 50mg | 74050-20-7 | 460.56 g/mol | C26H36O7 | 50 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a topical glucocorticoid supplied as a research/analytical standard for laboratory use. It is provided as a solid reference material (CAS 74050-20-7) for in vitro and analytical studies and is not intended for therapeutic use.
- Topical glucocorticoid for dermatoses research.
- Provided as a research/analytical standard for laboratory applications.
- CAS number 74050-20-7 and chemical formula C26H36O7.
- Molecular weight ~460.56 g/mol.
- Purity reported by vendors; consult the certificate of analysis before use.
- Available in multiple pack sizes, including 50 mg.
U.S. Pharmacopeia Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Medchemexpress LLC Dexamethasone acetate | 1177-87-3 | 98.2% | 434.50 | 1 G
Dexamethasone acetate is a glucocorticoid receptor agonist that significantly reduces expression of CD11b, CD18, and CD62L on neutrophils, and CD11b and CD18 on monocytes. It is effective in controlling COVID-19 infection and inhibits inflammatory microRNA-155 exosome production in lipopolysaccharide-induced macrophage responses.
- Functions as a glucocorticoid receptor agonist.
- Decreases CD11b, CD18, and CD62L expression on neutrophils and monocytes.
- Effective in controlling COVID-19 infection.
- Inhibits inflammatory microRNA-155 exosome production in macrophage responses.
- Targets: Glucocorticoid receptor, autophagy, mitophagy, SARS-CoV, and the complement system.
- Applicable in inflammation/immunology, endocrinology, and cancer research.
Apexbio Technology LLC Prednisone 53-03-2 1g
Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
Medchemexpress LLC Prednisone acetate-d3 | 125-10-0 | 96.5% | 403.48 | C23H25D3O6 | 10 MG
Prednisone acetate-d3 is the deuterium-labeled analog of prednisone 21-acetate used as a stable isotope internal standard for quantitative analysis by NMR, GC-MS, and LC-MS. It serves as a tracer in pharmacokinetic and metabolic studies and is supplied as a solid powder with storage recommendations for long-term stability.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS.
- Suitable tracer for pharmacokinetic and metabolic studies.
- High chemical purity (~96.5%) to support accurate quantitation.
- Solid powder form with recommended low-temperature storage for stability.
Medchemexpress LLC Fluocinolone Acetonide | 500 MG
Fluocinolone is a glucocorticoid receptor agonist. It is effective in preventing both lipid accumulation and inflammation. It can also promote the proliferation of DPCs and holds a potential role in repairing injured pulp tissues.
- Glucocorticoid receptor agonist
- Effective in preventing lipid accumulation and inflammation
- Promotes the proliferation of DPCs
- Potential role in repairing injured pulp tissues
- Used to study the prevention of chemotherapy-induced peripheral neuropathy